OBJECTIVES: To study the possible effectiveness of Babuna Sleep in producing effects on the central nervous system in laboratory rats, following techniques described in the literature.
BACKROUND: Tests described in the literature and those that we have carried out have as a goal the determination of a medication’s effect on the central nervous system. These effects are not limited to sedation, hypnotic, and tranquilizing, but also anti-depressive, which in high doses is known to prolong sleep induced by hexobarbitual or other barbiturates.
The loss of the righthening reflex is measured as the criteria of the duration of the sleep that is induced by the barbiturates. In this test mice are used since metabolic elimination is rapid in this species.
The present study has as background the possible sedative effect of Babuna Sleep.
As discussed in numerous international works, the pharmacological study of the above-mentioned effect is indispensable, and guarantees within the margin of error associated with the technique, that the potential for producing sedative effects in humans will be learned.
The basis of this work is the pharmacological effect as a sedative, as described in international literature .