Currently, in order to prevent and treat diseases of various etiology, including eco-logically causative agents, medi-cines based on such biologically active substances as polyphenols and polysaccharides have become common at the pharmaceutical market. Numerous studies have shown that medicines based on polysaccharides possess the im- mune-enhancing, antibacterial, an- tioxidant, hypolipidemic, wound- healing effects. Thick extracts of the plants studied contain a complex of bio- logically active substances main-ly polysaccharide with the con-tent ranging from 3.46 to 16.7%. In this case the study of the wound-healing activity of the bio- logically active substances com-plex of Inula Helenium and Inula Britannica is of current interest.