Establishment of the potential anti-inflammatory effect of the product known as PARSLEY, originating from NutraMedix Laboratories, LLC. Florida

The auricular edema is achieved by applying 12-0- Tetradecanoil Forbol-13 Acetate (TPA), one of the components responsible for the irritating action of croton oil, into the auditory pavilion of the mouse. The inflammatory reaction consists of erythema, edema and infiltration by polymorphonuclear leukocytes.  As such, eicosanoid-type mediators are freed, inducing degranulation of the mast cell6.  This technique thus allows the evaluation of the inhibiting substances of the biosynthesis of prostaglandins and leukotrienes.

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