The antioxidant capacity of methanolic crude extracts of Berberis vulgaris L., Cornus mas L. and Mahonia aquifolium Nutt. was tested with the thiobarbituric acid reactive substances formation assay, the ferric reducing power (FRAP) and 2,2-diphenyl-2-picrylhydrazyl (DPPH•) radical scavenging assay.

Atopic dermatitis is a chronic inflammatory disease of the skin which can significantly affect a patient’s health and well-being. Approximately 10 – 20% of children and 1 – 3% of adults are affected. The most common symptoms of atopic dermatitis are pruritus and erythema.

Alcoholic extracts of the antipsoriatic Mahonia aquifolium drug which were analysed for the irqualitative and quantitative alkaloid content, showed an in vitro inhibiting effect on cyclooxygenase (CO) of sheep seminal vesicles and 5-lipoxygenase (5-LO) of porcine leucocytes.

Mahonia aquifolium is an invasive woody evergreen shrub with sweet smelling bright yellow flowers that bloom in April. It has red-colored fruits that are often referred to as Oregon grapes. It is native to western North America, but it has spread to other areas of America, Australia and Europe and is used for landscaping and medicinal purposes.

Oxidative stress and inflammation are interlinked processes that seem to play an important role in aging. The present work aimed to test the antioxidant and anti-inflammatory activity of ethanolic Mahonia aquifolium leaves and bark extracts in an experimental acute inflammation.

Oxidative stress and inflammation are interlinked processes that seem to play an important role in aging. The present work aimed to test the antioxidant and anti-inflammatory activity of ethanolic Mahonia aquifolium leaves and bark extracts in an experimental acute inflammation.

The crude extract of Mahonia aquifolium (Berberidaceae) stem bark and its components berberine, palmatine and jatrorrhizine were screened for their inhibitory activity against a variety of dermatophytes and two Candida species of human origin using the in vitro dilution agar plate method.

The crude extract of Mahonia aquifolium (Pursh) Nutt. stem bark and its two main protoberberine alkaloids, berberine and jatrorrhizine, were tested for their in vitro antimicrobial activity. Twenty strains of coagulasenegative staphylococci and 20 strains of Propionibacterium acnes isolated from skin lesions of patients with a severe form of acne, and 20 strains of Candida sp. isolated from chronic vulvovaginal candidoses were tested for their susceptibility to crude extract and two isolated alkaloids.

Berberine and berberine-type alkaloids representing a structural class of organic cations, produced in numerous plants of the genera Berberis, Mahonia, and Coptis, have been shown to exert a broad spectrum of antimicrobial, anticancerogenic, and antimutagenic activity.

Mahonia root and stem bark have long been considered to have anti-inflammatory, anti-bacterial, anti-fungal activity and they are used particularly for treatment of skin diseases. They are indicated for treatment of the eczema, psoriasis, and other skin conditions.

A topical long-term treatment is for the most part unavoidable, since most psoriasis patients have to deal with their disease all life long. Therefore, it seems reasonable to look for new treatment strategies that would reduce the amount of risky medication.

As part of a study aimed at developing new pharmaceutical products from natural resources, the purpose of this research was twofold: to fractionate crude extracts from the bark of Mahonia aquifolium and to evaluate the strength of the antimutagenic activity of the separate components against one of the common direct-acting chemical mutagens.

Traditional Chinese medicine has been practised by Chinese communities world-wide for many generations, and there is a wealth of literature information available related to the therapeutic use of this type of medicine. In recent years, there has been a global surge in the popularity of herbal/traditional medicine, and currently there is enormous interest in developing new pharmaceutical products from such resources.

Atopic dermatitis is a common health problem that affects 15 million people in the United States. It usually begins in infancy, affecting 10% to 17% of children. Atopic dermatitis will improve in approximately50% of these children by the time they are between 5 and 15 years of age.

Mahonia aquifolium (Pursh) Nutt. from the Berberidacea family is a shrub widespread in the forests of the North American Pacific coast and is known also as a cultivated plant in gardens and parks called mahonia.

Psoriasis is a common skin disorder that affects more than 4.5 million people in North America. Treatment of psoriasis is problematic because the severity and distribution of psoriatic plaques varies immensely. Localized psoriasis can often respond to topical medications, of which steroid and vitamin D analogue creams such as calcipotriol, anthralin, coal tar, and ultraviolet light treatments are the most common.