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Sparga

An Antifungal Saponin from White Asparagus (Asparagus oflicinalis L) Bottoms

Asparagus is a familiar food as well as a medicinal plant in India and other countries. White asparagus is mostly processed into the canned product. For this purpose, the 'bottom cut' must be discarded because of its bitter taste, which is attributed to saponin constituents.

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Antifungal Activity of the Saponin Fraction Obtained from Asparagus officinalis L. and Its Active Principle

To date, many saponins have been isolated and characterized from asparagus. These constituents may have a bitter taste, and those parts which have a large amount of saponins in the 'bottom cut' must be discarded during processing.

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Antioxidant Activities and Caffeic Acid Content in New Zealand Asparagus (Asparagus officinalis) Roots Extracts

Asparagus officinalis are perennial plants that require re-planting every 10–20 years. The roots are traditionally mulched in the soil or treated as waste. The A. officinalis roots (AR) contain valuable bioactive compounds that may have some health benefiting properties.

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Antioxidant and antibacterial activities of ethanolic extracts of Asparagus officinalis cv. Mary Washington: Comparison of in vivo and in vitro grown plant bioactivities

Production of secondary metabolites using in vitro propagation techniques has been studied since the 1970s. For example, Al-Abta et al. (1979) showed that production of phthallides, the main flavour compounds of celery, can be detected in differentiated calli of celery plant but was undetected in the undifferentiated callus tissues. Based on several investigative studies, a compound produced in an in vivo plant could be produced at the same or different levels or not produced at all.

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Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats

Diet (nutrition) plays an important role in the management of diabetes, and for preventing and/or delaying the development of type 2 diabetes. Dietary approaches can be used alone (in the case of the onset of type 2 diabetes and in mild hyperglycaemia) or in combination with oral hypoglycaemic agents or insulin.

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Bioactive Compounds, Antioxidant and Binding Activities and Spear Yield of Asparagus officinalis L.

The aim of this investigation was to find a proper harvesting period and establishing fern number, which effects the spear yield, bioactive compounds and antioxidant activities of Asparagus officinalis L. Spears were harvested at 2, 4, and 6 weeks after sprouting.

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Domestic Processing of Onion Bulbs (Allium cepa) and Asparagus Spears (Asparagus officinalis): Effect on Flavonol Content and Antioxidant Status

Flavonols are of widespread occurrence in the most common edible fruits, vegetables, and seeds, and their content may reach up to a few hundred mg kg-1 of fresh weight. Berries such as bog whortleberry (Vaccinium uliginosum) and cranberry (Vaccinium oxycoccos) have been found to contain 184 and 263 mg kg-1 fresh weight of total flavonols, respectively.

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Effects of Asparagus officinalis Extracts on Liver Cell Toxicity and Ethanol Metabolism

Asparagus officinalis is a vegetable that is widely consumed worldwide and has also long been used as a herbal medicine for the treatment of several diseases. Although A. officinalis is generally regarded as a supplement for the alleviation of alcohol hangover, little is known about its effects on cell metabolism.

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Extraction and analysis of antioxidant compounds from the residues of Asparagus officinalis L.

Asparagus officinalis L., a well known healthy vegetable, which was named as “the king of vegetables” for its rich bioactive compounds, now is widely consumed all over the world. Bioactive components, such as flavonoid, lignan and steroidal saponin were found in this plant.

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Hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from Asparagus officinalis L. by-products in mice fed a high-fat diet

Hyperlipidaemia, including hypercholesterolaemia and hypertriglyceridaemia, is a major risk factor in the development of cardiovascular diseases. Indeed, the Lipid Research Clinics Coronary Primary Prevention Trial has concluded that every 1% reduction in plasma total cholesterol (TC) leads to a 2% decrease in the risk of coronary heart disease.

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Hypolipidemic Effect of n‐Butanol Extract from Asparagus officinalis L. in Mice fed a High‐fat Diet

During industrial processing of Asparagus (Asparagus officinalis L.), around half of each spear is discarded. However, these discarded asparagus (by‐products) might be used as food supplements for their potential therapeutic effects.

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In vitro antioxidant and antitumor activities of polysaccharides extracted from Asparagus officinalis

Ultrasonic circulating extractiontechnology was appliedfor thepolysaccharide extractionfromAsparagus officinalis. The crude polysaccharides were deproteinized by Sevag method and three main polysaccharide fractions, AOP-4, AOP-6 and AOP-8 were obtained by fractional precipitation with gradient concentrations of ethanol (40%, 60% and 80%).

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Isolation of a Novel Deoxyribonuclease with Antifungal Activity from Asparagus officinalis Seeds

A deoxyribonuclease distinct from the previously isolated asparagus ribosome-inactivating proteins, possessing a molecular weight of 30 kDa and requiring a pH of 7.5 for optimum hydrolytic activity toward herring sperm DNA, was isolated from Asparagus officinalis seeds.

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Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model

Shoots of white asparagus are a popular vegetable dish, known to be rich in many bioactive phytochemicals reported to possess antioxidant, and anti-inflammatory and antitumor activities. We evaluated the anticancer mechanisms of a methanolic extract of Asparagus officinalis L. shoots (Asp) on human colon carcinoma cells (SW480) and their derived metastatic cells (SW620), and Asp chemopreventive properties were also assessed in a model of colon carcinogenesis.

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Review on Therapeutic and Pharmaceutically Important Medicinal Plant Asparagus officinalis L

The use of medicinal plants is as old as human civilization. About 600-700 plants species in Pakistan are used for preparation of ayurvedic, unani and homeopathic drugs. Asparagus officinalis a sub-erect prickly shrub with white tuberous root usually is of prime importance in this regard.

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Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway

The global burden of cancer is still increasing and it is the leading cause of death in economically developed countries. About 12.7 million new cases and 7.6 million cancer deaths are estimated to have occurred in 2008 worldwide. Most cancers can be cured surgically before cancer metastasis, and 5 year survival rates are often above 90%.

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Steroids from the Roots of Asparagus officinalis and Their Cytotoxic Activity

One new (Sarsasapogenin O) and seven known steroids were isolated from the roots of Asparagus officinalis L. Their structures were elucidated on the basis of spectroscopic analysis, including various 2D-NMR techniques, hydrolysis, and by comparison of spectral data of known compounds.

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Study of the acute oral toxicity of Sparga

Sparga will be used in humans because of the vital importance of carrying out these first-step tests. They will not only guarantee the quality of the product, but will also establish that there are no adverse side effects in humans who take the product.

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The aqueous extract of Asparagus officinalis L. by-product exerts hypoglycaemic activity in streptozotocin-induced diabetic rats

BACKGROUND: The inedible bottom part of asparagus (Asparagus officinalis L.) spears, around one-third to one-half of the total length, is always discarded as by-product. Since it still contains various bioactive substances, this by-product might have potential usage in food supplements for its therapeutic effects. In this study the hypoglycaemic effect of the aqueous extract of asparagus by-product (AEA) was evaluated in a streptozotocin (STZ)-induced diabetic rat model.

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Two new phenolic compounds and antitumor activities of asparinin A from Asparagus officinalis

Asparagus officinalis is a dioecious plant which is well known as a popular vegetable at home and abroad [1]. It is also used as a traditional Chinese medicine because of its chemical composition of various activities [2], including saponins [3], saccharides [4], flavonoids [5], acetylenic compounds [6], and sulfur-containing [7] and nitrogen-containing [8] compounds

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