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Hormonal Balance

Acute and Chronic Dosing of Lepidium meyenii (Maca) on Male Rat Sexual Behavior

The use of natural remedies for the treatment of sexual disorders is under current investigation. For generations people of the rural community in Peru have used Lepidium meyenii Walpers (Maca), because of their belief that it improves fertility and sexual desire.

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An in vitro evaluation of Tribulus terrestris L. fruit extract for exploring therapeutic potential against certain gut ailments

The enteric pathogens and oxidative stress are known to generate intestinal inflammation, chronic gut ailments and oncogenesis. Modulation of the gut microbial peak populations through herbal agents, offers a promising therapeutic modality.

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Anti-stress effects of the "tonic" Ptychopetalum olacoides (Marapuama) in mice

With the recognition that high levels of sustained stress are associated with the natural course of countless illnesses, effective anti-stress agents have gained importance. Improved endurance to particularly stressful periods is one of the medicinal claims for Marapuama (Ptychopetalum olacoides Bentham, PO). a popular Amazonian herbal. The purpose of this study was to evaluate if PO possesses anti-stress properties.

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Antibacterial activity of Eurycoma longifolia Jack

Objective: To evaluate methanolic, ethanolic, acetone and aqueous extracts from different parts of Eurycoma longifolia (E. longifolia) (leave, stem, and root) for antibacterial activity against Gram-positive and Gram-negative bacteria and to utilize the leaves and stem parts rather than the root, which is already used for male sexual enhancement in Malaysia.

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Antibacterial activity of medicinal plants of Northern Peru – can traditional applications provide leads for modern science?

Bacterial infections and inflammation are among the ailments treated by traditional healers. The World Health Organization has expressed high interest in traditional medicine, and it is important to demonstrate scientifically that remedies employed in folk medicine are indeed therapeutically active. In this communication, antibacterial assays for 165 plant species conducted under simple laboratory conditions in a private clinic in Trujillo, Peru has been reported.

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Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq

Traditional medicine has been practiced for many centuries by a substantial proportion of the population of Iraq. The interest in the study of medicinal plants as a source of pharmacologically active compounds has increased worldwide. It is recognized that in some developing countries, plants are the main medicinal source to treat infectious diseases.

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Antifungal activities and action mechanisms of compounds from Tribulus terrestris L.

Antifungal activity of natural products is being studied widely. Saponins are known to be antifungal and antibacterial.

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Antioxidant activities of Ptychopetalum olacoides in mice brain

Ptychopetalum olacoides (PO) roots are used by Amazonian peoples to prepare traditional remedies for treating various central nervous system conditions in which free radicals are likely to be implicated.

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Antioxidant activity of Tribulus terrestris—a natural product in infertility therapy

Antioxidant potential of Tribulus terrestris L. herbal preparations was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) di-ammonium salt (ABTS) free radicals, ferric reducing antioxidant power (FRAP) and inhibition of lipid peroxidation by ferric thiocyanate method (FTC).

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Antioxidant activity of the cruciferous vegetable Maca

Maca (Lepidium meyenii) is a plant from the Andes of Peru. Maca is used as a food for its nutritional value and ethnomedicinal properties linked to fertility and vitality. The purpose of this study was to evaluate the antioxidant activity of Maca. For all experiments an aqueous extract of Maca was used.

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Antioxidant and Anti-inflammatory Activity of Eurycoma Longifolia Jack, A Traditional Medicinal Plant in Malaysia

Tongkat Ali (Eurycoma longifolia Jack, family, Simaroubaceae) is traditionally used in Malaysia as health supplement for hypertension, diarrhea, aches, persistent fever, malaria, sexual insufficiency, dysentery, and glandular swelling. In this study, hydroalcoholic extract of Eurycoma longifolia Jack was studied for its antioxidant and in-vitro anti-inflammatory properties.

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Antiviral activity of maca (Lepidium meyenii) against human influenza virus

Objective: To investigate antiviral activity of maca to reduce viral load in Madin-Darby canine kidney (MDCK) cells infected with influenza type A and B viruses (Flu-A and Flu-B, respectively).

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Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack

Eurycoma longifolia Jack (Simaroubaceae), which is known as `Tongkat Ali' or Ali's walking stick in Malaysia, is a plant that grows to a height of 10 m with a branch diameter of 10 cm. It is found in primary and secondary, evergreen and mixed deciduous forests in Burma, Indochina, Thailand, Malaysia, Sumatra, Borneo and the Phillipines. It is popularly used, singly or as an essential component, in herbal remedies, for various illnesses including fevers, aches, sexual insufficiency, hypertensive, tuberculosis, vermifuge and as health supplement.

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Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats

Tribulus terrestris (TT) has long been used in the traditional Chinese and Indian systems of medicine for the treatment of various ailments and is popularly claimed to improve sexual functions in man. Sexual behaviour and intracavernous pressure (ICP) were studied in both normal and castrated rats to further understand the role of TT containing protodioscin (PTN) as an aphrodisiac.

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Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content

Objective: To examine the estrogenic and androgenic activity of Lepidium meyenii (Maca) and its effect on the hormonal profile and symptoms in postmenopausal women.

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Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia

Eurycoma longifolia, native to Burma, Indochina, Thailand, and Southeast Asia is a tall Simaroubaceous slender shrub-tree commonly found as an understroy in the lowland forests at up to 500 m above sealevel. E. longifolia known locally as ‘Tongkat Ali’ in Malaysia, ‘Pasakbumi’ in Indonesia, ‘Cay ba binh’ in Vietnam and ‘Ian-don’ in Thailand is popularly sought after in herbal remedies and has been frequently prescribed either as a single ingredient or as a mixture with other herbs.

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Effect of Black maca (Lepidium meyenii) on one spermatogenic cycle in rats

Lepidium meyenii (Maca) grows exclusively between 4000 and 4500 m above sea level in the Peruvian central Andes. The hypocotyls of this plant are traditionally used in the Andean region for their supposed fertility-enhancing properties.

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Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men

This study was a 12-week double blind placebo-controlled, randomized, parallel trial in which active treatment with different doses of Maca Gelatinizada was compared with placebo. The study aimed to demonstrate if effect of Maca on subjective report of sexual desire was because of effect on mood or serum testosterone levels.

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Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)

Lepidium meyenii (Maca) is a Peruvian hypocotyl that grows exclusively between 4000 and 4500 m in the central Andes. Maca is traditionally employed in the Andean region for its supposed fertility-enhancing properties.

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Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men

Lepidium meyenii (Maca) is a Peruvian hypocotyl that grows exclusively between 4000 and 4500 m in the central Andes. Maca is traditionally employed in the Andean region for its supposed aphrodisiac and/or fertility-enhancing properties.

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Effect of a Lipidic Extract Lepidium meyenii on Sexual Behavior in Mice and Rats

Objectives: To determine the effect of oral administration of a purified lipidic extract from Lepidium meyenii (MacaPure M-01 and M-02) on the number of complete intromissions and mating in normal mice, and on the latent period of erection (LPE) in rats with erectile dysfunction.

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Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection

Tribulus terrestris has been used as an aphrodisiac. However, little is known about the effects and mechanism of action of T. terrestris on penile erection. Therefore, the effect of a T. terrestris extract and the mechanism of action of the extract on relaxation of the corpus cavernosum (CC) were investigated. The erectogenic effects of an oral preparation of the extract were also assessed.

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Effects of Eurycoma longifolia Jack (Tongkat Ali) on the Initiation of Sexual Performance of Inexperienced Castrated Male Rats

The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days.

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Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats

The word aphrodisiac is derived from ‘Aphrodite’, the Greek goddess of love, beauty and sexuality, and aphrodisiacs are the substances which stimulate sexual desire. The possibility of bioactive aphrodisiacs which may be derived from plants, animals or minerals, bas been attractive throughout recorded history.

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Effects of Lepidium meyenii Walp and Jatropha macrantha on Blood Levels of Estradiol-17β, Progesterone, Testosterone and the Rate of Embryo Implantation in Mice

The effects of two Peruvian folk medicines, Lepidium meyenii Walp and Jatropha macrantha, on mouse sex steroid hormones and embryo implantation were investigated. Progesterone levels increased significantly in mice that received L. meyenii Walp, while testosterone levels increased significantly in mice that received L. meyenii Walp as well as in those that received both L. meyenii Walp and J. macrantha.

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Eurycoma Iongifolia Increases Sexual Motivation in Sexually Naive Male Rats

The aim of this study is to provide evidence on the aphrodisiac property of Eurycoma Iongifolia Jack. An electric grid was used as an obstruction in the electrical copulation cage in order to determine how much an aversive stimulus the sexually naive male rat for both the treated with E. Iongifolia Jack and control groups were willing to overcome to reach the estrous receptive female in the goal cage.

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Eurycoma longifolia Jack Enhances Libido in Sexually Experienced Male Rats

The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days.

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Eurycoma longifolia Jack and Orientation Activities in Sexually Experienced Male Rats

Eurycoma longifolia Jack (Simaroubaceace), identified by its local name as Tongkat Ali, is commonly found along the hilly jungle slopes of Malaysia. Over the years, pharmacological evaluations of the various compounds isolated from this plant showed that it possessed antimalarial, cytotoxic, antiulcer, and antipyretic, properties.

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Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis

Eurycoma longifolia Jack (Simaroubaceae family), known locally as ‘Tongkat Ali’ by the ethnic population, is popularly taken as a traditional remedy to improve the male libido, sexual prowess and fertility. Presently, many tea, coffee and carbonated beverages, pre-mixed with the root extract are available commercially for the improvement of general health and labido.

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Extraction, purification and antioxidant activities of the polysaccharides from maca

Water-soluble polysaccharides were separated from maca (Lepidium meyenii) aqueous extract (MAE). The crude polysaccharides were deproteinized by Sevag method. During the preparation process of maca polysaccharides, amylase and glucoamylase effectively removed starch in maca polysaccharides.

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Immunomodulatory effects of a polysaccharide purified from Lepidium meyenii Walp. on macrophages

A polysaccharide (MP21) was extracted and purified from Lepidium meyenii Walp. using DEAE-52 and SephacrylTM S-500 columns. Its physicochemical properties and macrophage immunomodulatory activity were investigated in vitro. T

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In Vitro and in Vivo Antifungal Activities of the Eight Steroid Saponins from Tribulus terrestris L. with Potent Activity against Fluconazole-Resistant Fungal

In recent twenty years, the risk of opportunistic fungal infections has greatly increased in patients who are severely immunocompromised due to cancer chemotherapy, organ or bone marrow transplantation, and human immunodeficiency virus infection.

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In vitro anti-tumor promoting and anti-parasitic activities of the quassinoids from Eurycoma longifolia

Some quassinoids (1-6) isolated previously as plant growth inhibitors from the leaves of Eurycoma longifolia Jack. (Simaroubaceae) were subjected to in vitro tests on anti-tumor promoting, antischistosomal and plasmodicidal activities.

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Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats

The root of Eurycoma longifolia Jack, native to South East Asia, has long been used as a male aphrodisiac remedy to treat sexual disorders.

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Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice

Aim: To observe the effect of the aqueous extract of hypocotyls of the plant Lepidium meyenii (Maca) on spermatogenic damage induced by the organophosphate insecticide malathion in mice.

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Lepidium meyenii (Maca) reversed the lead acetate induced — Damage on reproductive function in male rats

Rats were treated with 0, 8, 16 and 24 mg/kg of lead acetate (LA) (i.p.) for 35 days with or without Maca. Maca was co-administrated orally from day 18 to day 35. The lengths of stages of the seminiferous epithelium were assessed by transillumination.

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Lepidium meyenii Walp. improves sexual behaviour in male rats independently from its action on spontaneous locomotor activity

The aim of the present study is to determine the effect of acute and chronic oral administration of a purified extract from L. meyenii root on male rats sexual performances and spontaneous locomotion.

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Maca (Lepidium meyenii) for treatment of menopausal symptoms: A systematic review

Maca (Lepidium meyenii), an Andean plant of the brassica (mustard) family has been used for centuries in the Andes as an adaptogenic plant to manage anemia, infertility and female hormone balance. The aim of this review was to assess the evidence for and against the effectiveness of the maca plant as a treatment for menopausal symptoms.

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Medicinal property, phytochemistry and pharmacology of several Jatropha species (Euphorbiaceae)

The genus Jatropha that belongs to tribe Joannesieae in the Euphorbiaceae family contains approximately 170 known species. The name Jatropha is derived from the Greek word ‘‘jatros’’ (doctor) and ‘‘trophe’’ (food), which implies its medicinal uses.

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Memory retrieval improvement by Ptychopetalum olacoides in young and aging mice

Cognitive deficits are often observed in old humans, as well as in various neurological conditions. It has been previously proposed that memory retrieval in the elderly appears to be more impaired than acquisition or storage. Moreover, the first symptoms in Alzheimer’s disease include impairment of new information storage or retrieval.

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Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men

Sexual health is an important issue in quality of life of males and females. In males’ sexual well-being, dissatisfaction in sexual life is significantly caused by erectile dysfunction (ED), which is defined as a consistent or recurrent inability of a man to attain and/or maintain penile erection sufficient for sexual activity.

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Sexual Effects of Puncturevine (Tribulus terrestris) Extract (Protodioscin): An Evaluation Using a Rat Model

Apart from its claims for improvement of sexual functions in men, the puncturevine plant (Tribulus terrestris: TT) has long been considered as an energizer and vitalizer in the indigenous system of medicine. Sexual behavior and intracavernous pressure (ICP) measurements were taken in rats to scientifically validate the claim of TT [containing protodioscin (PTN)] as an aphrodisiac.

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Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism?

In most countries, millions of people are relying on herbal medicines as remedy for numerous ailments. In South-East Asia, Eurycoma longifolia Jack, also known as ‘Malaysian ginseng’ or Tongkat ali, is used to combat stress and disease and to improve physical strength.

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Studies on the Anxiolytic Activity of Eurycoma longifolia Jack Roots in Mice

Eurycoma longifolia Jack, from the Simaroubaceae family and identified locally as 'Tongkat Ali', is found in primary and secondary, evergreen and mixed deciduous forests in Burma, Indochina, Thailand, Malaysia, Sumatra, Borneo and the Philippines. It is popularly sought after as a singly or an essential component for the treatment of fevers, aches, sexual insufficiency and also as health supplements, but has not been indicated strongly for any specific illness.

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Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction

Lepidium meyenii (Maca) is a cultivated root belonging to the brassica family used in the Andean region for its supposed aphrodisiac properties. We carried out a double-blind clinical trial on 50 Caucasian men affected by mild erectile dysfunction (ED), randomised to treatment with Maca dry extract, 2400 mg, or placebo.

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The Influence of Maca (Lepidium meyenii) on Antioxidant Status, Lipid and Glucose Metabolism in Rat

This work focused on the effect of maca on lipid, anti-oxidative, and glucose parameters in hereditary hypertriglyceridemic (HHTg) rat. Maca (1%) was administred to rats as a part of a high-sucrose diet (HSD) for 2 weeks. Rosiglitazone (0.02%) was used as a positive control.

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The Protective Effect of Tribulus terrestris in Diabetes

Tribulus terrestris L (TT) is used in the Arabic folk medicine to treat various diseases. The aim of this article was to investigate the protective effects of TT in diabetes mellitus (DM). Diabetes is known to increase reactive oxygen species (ROS) level that subsequently contributes to the pathogenesis of diabetes.

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The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction - an evaluation using primates, rabbit and rat

Hormonal effects of Tribulus terrestris (TT) were evaluated in primates, rabbit and rat to identify its usefulness in the management of erectile dysfunction (ED). TT extract \Vas administered intravenously, as a bolus dose or 7.5. 15 and 30 mg kg. in primates for acute study.

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Traditional knowledge for modern ailments – plants used for the treatment of diabetes and cancer in Northern Peru

Various cancers and tumorous conditions were treated by healers. A total of 47 plant species belonging to 42 genera and 30 families were documented and identified as anti-cancer and anti-diabetic herbal remedies in Northern Peru, with 31 plants used for diabetes treatment and 17 species used for conditions identified by local healers as cancer.

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Tribulus terrestris fruit extract improves antioxidant defense in female reproductive tract: A comprehensive study in diabetic rats

Diabetes mellitus (DM), an endocrine metabolic disorder of multiple etiologies is characterized by chronic hyperglycemia with impaired carbohydrate, fat and protein metabolism resulting from abnormal insulin production/action.

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