UP
FOR PROMTING JOINT HEALTH AND IMPROVED PROTIEN DIGESTION
Bromelain is a natural enzyme extract derived primarily from the stems of pineapples (Ananas comosus). Known for its proteolytic (protein-digesting) activity, bromelain has been widely used both in the culinary world as a meat tenderizer and in health and wellness settings as a supplement to support various physiological functions. Unlike many enzymes that are active only in the digestive tract, bromelain can be absorbed in the body and remain active in the bloodstream, making it a versatile compound with systemic effects.
Traditionally, bromelain has been recognized for its role in supporting healthy inflammation and aiding recovery from minor injuries, surgeries, or intense physical exertion. It is believed to help modulate the body's inflammatory response, which can be beneficial for maintaining joint comfort, sinus health, and overall tissue wellness. Additionally, bromelain may support cardiovascular health by helping maintain normal blood viscosity and supporting healthy circulation.
ANTI-INFLAMMATORY
ANALGESIC
ANTIEDEMATOUS
FIBRINOLYTIC
ANTITHROMBOTIC
MUCOLYTIC
DIGESTIVE
IMMUNOMODULATORY
ANTIMICROBIAL
WOUND-HEALING
ANTIOXIDANT
DECONGESTANT
CARDIOPROTECTIVE
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Rathnavelu, V., Alitheen, N. B., Sohila, S., Kanagesan, S., & Ramesh, R. (2016). Potential role of bromelain in clinical and therapeutic applications: A review. Biomedical Reports, 5(3), 283–288. Full Article
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Kasemsuk, T., Saengpetch, N., Sibmooh, N., & Unchern, S. (2016). Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clinical Rheumatology, 35(9), 2531–2540. Full Article
Klein, G., Kullich, W., Schnitker, J., & Schwann, H. (2006). Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomized study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clinical and Experimental Rheumatology, 24(1), 25–30.
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Chakraborty, A. J., Mitra, S., Tallei, T. E., Tareq, A. M., Nainu, F., Cicia, D., Dhama, K., Emran, T. B., Simal-Gandara, J., & Capasso, R. (2021). Bromelain a potential bioactive compound: A comprehensive overview from a pharmacological perspective. Life, 11(4), 317. Full Article
Colletti, A., Li, S., Marengo, M., Adinolfi, S., & Cravotto, G. (2021). Recent advances and insights into bromelain processing, pharmacokinetics and therapeutic uses. Applied Sciences, 11(18), 8428. Full Article
Hikisz, P., & Bernasinska-Slomczewska, J. (2021). Beneficial properties of bromelain. Nutrients, 13(12), 4313. Full Article
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Insuan, O., Janchai, P., Thongchuai, B., Chaiwongsa, R., Khamchun, S., Saoin, S., Insuan, W., Pothacharoen, P., Apiwatanapiwat, W., Boondaeng, A., & Vaithanomsat, P. (2021). Anti-inflammatory effect of pineapple rhizome bromelain through downregulation of the NF-κB- and MAPKs-signaling pathways. Current Issues in Molecular Biology, 43(1), 93–106. Full Article
Arweiler, N. B., et al. (2011). Influence of Scutellaria baicalensis extract on the initial oral biofilm in humans. Archives of Oral Biology, 56(7), 728–732.
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Kostiuchenko, O., Kravchenko, N., Markus, J., Burleigh, S., Fedkiv, O., Cao, L., Letasiova, S., Skibo, G., Fåk Hållenius, F., & Prykhodko, O. (2022). Effects of proteases from pineapple and papaya on protein digestive capacity and gut microbiota in healthy C57BL/6 mice and dose-manner response on mucosal permeability in human reconstructed intestinal 3D tissue model. Metabolites, 12(11), 1027. Full Article
Babazade, H., Mirzaagha, A., & Konarizadeh, S. (2023). The effect of bromelain in periodontal surgery: A double-blind randomized placebo-controlled trial. BMC Oral Health, 23, 286. Full Article
Shing, C. M., Chong, S., Driller, M. W., & Fell, J. W. (2016). Acute protease supplementation effects on muscle damage and recovery across consecutive days of cycle racing. European Journal of Sport Science, 16(2), 206–212. Full Article
Take one to two capsules one to two times daily (at least 30 min. before meals) with a full glass of water or as directed by your physician
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