EZOV

Leishmaniasis is a parasitic disease transported by sand flies. In this study, we evaluated the efficacy of herbals and compared with systemic glucantime against cutaneous leishmaniasis in Balb/c mice.

Hyssopus officinalis (L) (Hyssop, Family: Lamiaceae), one of the endemic Iranian perennial herb with a long history of medicinal use, was studied to detect some biologically active chemical constituents of the plant.

Hyssopus officinalis L. has been traditionally used for its antiseptic properties in treatment of infectious disorders. In order to confirm its antiseptic properties with respect to traditional uses, we have screened the antimicrobial activity of aerial parts of H. officinalis.

Through this work shed light on the importance of medicinal plants and natural products, which are important sources of biologically active substances of medical interest? And especially shed light on Hyssopous officinalis.

Several research publications are published on the medicinal plant Hyssopus officinalis L. But, the researchers find quite a difficulty to study all the publications in a short while. The present review was designed to compile and summarize all the published works on the medicinal plant H. officinalis L. traditionally used in several systems of medicine (1885-2018).

The present study investigated the effect of H. officinalis essential oil on avoidance memory in chronic stress-induced. Mice were exposed to chronic immobilization stress and were treated with H. officinalis essential oil for 21 days.

The relationships between salt stress and antioxidant enzymes activities, proline, phenol and anthocyanine contents in Hyssopus officinalis L. plants in growth stage were investigated. The plants were subjected to five levels of saline irrigation water, 0.37 (tap water as control) with 2, 4, 6, 8 and 10 dSm–1 of saline water.

Hyssopus officinalis L. is a well-known herb for its culinary and medicinal significance. The purpose of this study was to perform the pharmacognostic evaluation.

Nowadays, there's a growing demand for the natural antioxidants due to the harmful effects of synthetic antioxidants. Therefore, introduction of new natural antioxidants (especially those with plant origin) is very important.

Leishmania is transmitted by sandflies that ingest the parasite in the amastigote phase resident within macrophages, then inoculate the promastigote phase into body hosts. The present study was conducted to evaluate the in vitro effects of alcoholic extract of Plants on L.major

Hyssopus officinalis L. is a common plant that is most usually found in three color forms - f. cyaneus (blue), f. ruber Mill. (purple/pink) and f. albus Alef (white). In the present work, we evaluated the chemical composition and antimicrobial activity of essential oils obtained from Polish-sourced white- and pink-flowered H. officinalis.

Hyssopus officinalis L. (Hyssop) is one of the most popular herbal preparations, mainly distributed in the East Mediterranean to central Asia. The plant has been used traditionally for medicinal purposes; generally, these therapeutic uses and health benefits of hyssop are largely based on folklore rather than on scientific substantiation, making it a good candidate to gather documentations, including the phytochemical content, in vitro experiments, animal models and human studies available in the recent scientific studies.

Herpes simplex virus (HSV) infection is a major opportunistic infection in immunosuppressed persons. The development of resistant strains of HSV to the available drugs for infection management, as is evident in the first drug of choice acyclovir, has further compounded this situation. There is therefore an urgent need to identify and develop new alternative agents for management of HSV infections, more so, for those due to resistant strains.

Terrestrial plants have long been considered to be a rich source of biologically active secondary metabolites. Previously many plants belonging to the mint family (Labiatae) showed antiviral activity against a number of viruses, including HIV-1. Tannins found in mint plant extracts and as secondary metabolites in food, including tea have been shown to have moderate anti-HIV activity.

Hyssopus officinalis L. var. decumbens (Lamiaceae) is a plant growing in Provence, France. Our recent studies show that the essential oil obtained from its aerial parts has in vitro antimicrobial activity, due mainly to one of its chemical components, linalool (Mazzanti et al., in press).

The objective of this work was to study the ability of rosemary and hyssop extracts to inhibit lipid oxidation and metmyoglobin formation in pork meat, thereby stabilizing meat color. We also evaluated their effects on iron release from the heme moiety of pork meat.

This study was designed to examine the in vitro antioxidant and antimicrobial activities and to characterize the polyphenolic composition of the ethanolic extracts of Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys. Qualitative and quantitative analysis of the major phenolic compounds were conducted using high-performance liquid chromatography coupled to mass spectrometry (HPLC-MS). The total polyphenols, caffeic acid derivatives and flavonoids content was spectrophotometrically determined.

Hyssop, Hyssopus officinalis (Lamiaceae) is one of the most important pharmaceutical herbs that extensively cultivated in central and south European countries such as Russia, Spain, France and Italy (Omidbaigi, 2000). Despite having a bitter taste, it is used as a food flavor and in sauce formulations (Kazazi et al., 2007).

In this study, antioxidant and antihemolytic activities of ethanolic extract of flowers, leaves, and stems of Hyssopus officinalis L. Var. angustifolius were investigated employing different in vitro assay systems.

The essential oil of hyssop is widely used in food, pharmaceutical and cosmetic industries throughout the world. Therefore, it is very important to know the chemical characteristics of the oil for economic use and enhanced performance of the end products. This study was carried out to determine antimicrobial and antioxidant activities of the essential oil of Hyssopus officinalis (L.) (Lamiaceae) collected from wild in the Southeast Anatolian, Turkey.

The aim of the study was to investigate the chemical composition of Hyssopus officinalis L. subsp. pilifer (Pant.) Murb. essential oil (EO) and deodorized extracts (DE) and to evaluate their potential antifungal and antioxidant activities.

The antimicrobial activity of essential oil of Hyssopus ocinalis L. var decumbens (Jordan & Fourr.) Briq. from France (Banon) and Hyssopus ocinalis L. from Italy (Piedmont) was studied taking account of their chemical composition determined by GC and GC–MS.

Leishmania is transmitted by sandflies that ingest the parasite in the amastigote phase resident within macrophages, then inoculate the promastigote phase into body hosts. The present study was conducted to evaluate the in vitro effects of alcoholic extracts of plants on L. major. The extract of aerial parts of plants were obtained by maceration. The in vitro experiments were performed on promastigotes to assess anti Leishmanial activity of the extracts using glucantime as a reference.

The Uygur herb, Hyssopus officinalis L., has been demonstrated to affect the levels of a number of cytokines in asthmatic ,nice, including interleukin-4, -6 and -17 and interferon-y. In the present study, the effect of Hyssopus officinalis L. on airway immune regulation and airway inflammation was investigated in a mouse model of chronic asthma. A total of 32 BALB/c mice, were randomly divided into four groups, which included the normal, chronic asthmatic, dexamethasone treatment and Hyssopus officinalis L. treatment groups.

Crude extracts of dried leaves of Hyssop officinalis showed strong anti-HIV activity as measured by inhibition of syncytia formation, HIV reverse transcriptase (RT), and p17 and p24 antigen expression, but were non-toxic to the uninfected Molt-3 cells. Ether extracts from direct extraction (Procedure I), after removal of tannins (Procedure II), or from the residue after dialysis of the crude extract (Procedure III), showed good antiviral activity

The antifungal and fungicidal e€ects of hyssop (Hyssopus ocinalis) oil and its individual components were studied in a series of in vitro and in vivo experiments. Mycelial growth of the plant pathogenic fungi Pyrenophora avenae and Pyricularia oryzae was completely inhibited by 0.4% hyssop oil. Volatile components di€using from agar medium containing 0.4% hyssop oil also completely inhibited the growth of these two fungi.

The aim of the study was to investigate the chemical composition of Hyssopus officinalis L. subsp. pilifer (Pant.) Murb. essential oil (EO) and deodorized extracts (DE) and to evaluate their potential antifungal and antioxidant activities.

The two essential oils isolated from plants of hyssop (Hyssopus officinalis L. ssp. officinalis) grown in two different localities near Urbino (Marche, Italy) were analyzed by GC and GC/MS. The major components were pinocamphone (34% and 18.5%), isopinocamphone (3.2% and 29%) and β-pinene (10.5% and 10.8%).

The chemical composition of hyssop oil from Bulgaria was determined by gas chromatography with flame ionization detection and gas chromatography
mass spectrometry on two different chromatographic columns. The quantity of identified compounds was shown correspond to 97.2% and 98% of the total oil content.